Best Laser Treatment for Acne Scars: Comparing Your Options (and Why Combination Therapy Wins)

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Acne scars are not one problem. They are a mix of texture loss, tethering bands, uneven pigment, enlarged pores, and redness. One device rarely covers every layer. In real clinical practice, the best outcomes come from a plan that matches scar type, skin type, downtime tolerance, and risk profileโ€”then uses the right tools in the right sequence. 

Atย Dermablue, our highest-yield approach for most patients combines three categories: fractional CO2 resurfacing (eCO2), RF microneedling, andย Lutronicย ULTRA (1927 nm thulium) for texture + tone refinement. This combination targets collagen remodeling from multiple angles while helping us control downtime and pigment risk.ย ย 

Start Here: What Kind of Acne Scars Do You Have?ย 

Most acne scars fall into a few patterns:ย 

  • Ice pick scars: narrow, deep โ€œpuncturesโ€ย 
  • Boxcar scars: wider, sharper edgesย 
  • Rolling scars: soft depressions from tetheringย 
  • Hypertrophic scars: raised scars (less common on face)ย 
  • Post-inflammatoryย hyperpigmentation (PIH): brown discoloration after acneย 
  • Post-inflammatoryย erythema (PIE): persistent red marksย 

Your scar mix determines your best treatment mix. 

Option 1: Fractional CO2 Laser (eCO2) โ€”ย Best forย Deep Texture Changeย 

Fractional CO2 is an ablative resurfacing laser. It creates controlled micro-injuries and heat columns in skin, which drives collagen remodeling and scar edge softening. Thisย remainsย one of the most effective tools for moderate-to-severe atrophic scars, especially boxcar and mixed atrophic patterns.ย ย 

Why we use it:ย 

  • Strongest โ€œtexture resetโ€ per treatment session for many patientsย 
  • Improves scar depth, pore appearance, and overall roughnessย 
  • Often becomes the anchor treatment when scars feel โ€œetched inโ€ย 

Typical course: 1โ€“3 sessions for many patients, sometimes more for deep scarring

Downtime: commonly 5โ€“10 daysย of visible recovery depending on intensityย 

Common short-term effects: redness, swelling, bronzing, peelingย 

Key risk to manage:
PIH risk rises in deeper skin tones or with sun exposure, so settings, priming, and aftercare matter. eCO2 is a Cynosureย Lutronicย platform designed for fractional CO2 resurfacing flexibility.ย ย 

Option 2: RF Microneedling โ€” Best for Rolling Scars and Collagen Remodelingย Withย Less Surface Downtime

RF microneedling delivers heat through insulated or semi-insulated needles below the surface, targeting dermal remodeling while keeping more of the epidermis intact compared with ablative laser. Evidence supports meaningful improvement in atrophic acne scars with a favorable downtime profile for many patients.ย ย 

Why we use it:ย 

  • Excellent for rolling scars and โ€œsoft valleysโ€ย 
  • Useful across many skin tones when performed thoughtfullyย 
  • Can be paired in a sequence with CO2 to improve total correctionย 

Typical course: 3โ€“6 sessionsย 

Downtime: often 1โ€“3 days of redness and mild swelling; varies by depth/energyย 

Key risk to manage:
RF microneedling is a medical procedure. The FDA issued a safety communication on potential serious complications reported with certain uses (burns, scarring, fat loss, nerve injury). Provider training, anatomy knowledge, device choice, and parameter discipline drive safety.ย ย 

Our clinical takeaway:
RF microneedling can be high value when done by experienced medical teams using conservative, anatomically informed protocols.ย 

Option 3:ย Lutronicย ULTRA (1927 nm Thulium) โ€” Best for โ€œFinishing Workโ€: Tone, Texture Refinement, and Blending

ULTRAย isย a non-ablative fractional thulium laser (1927 nm). It creates microchannels and fractional heat zones that can improve fine texture, dyschromia, and overall skin quality with less downtime than ablative resurfacing. It is not the strongest tool for deep, tethered scars, but it is excellent for blending, tone correction, and incremental texture gainsโ€”especially when scars come with pigment issues.ย ย 

Why we use it:ย 

  • Helps even tone and โ€œpolishโ€ texture after deeper remodeling treatmentsย 
  • Useful when PIH risk requires a less aggressive surface approachย 
  • Strong option for patients wanting minimal downtime, gradual improvementย 

Typical course: 3โ€“5 sessionsย 

Downtime: usually mild redness and dryness for a few daysย 

Best suited for: mild-to-moderate scarring, pigment issues, and refinement phasesย 

Why Combination Therapy Usually Produces the Best Acne Scar Resultsย 

Acne scars live at different depths. CO2 addresses scar edges and surface architecture. RF microneedling targets deeper dermal collagen remodeling and tethering-related contour changes. ULTRA helps refine tone and micro-texture, which makes scars less noticeable even when depth improves modestly.ย 

This layered strategy often produces a more natural result than overusing one modality. It also lets us dial downtime up or down across a treatment series, instead of forcing every session to be a major recovery event. Evidence supports fractional CO2 benefits for atrophic scars, and published reviews support RF microneedling as an effective modality for acne scarring.  

What a Smart Treatment Plan Looks Likeย 

Most patients do best with a phased plan:ย 

Phase 1: control acne and inflammation (active breakouts reduce results and raise risk)ย 

Phase 2: deeper remodeling (eCO2 and/or RF microneedling depending on scar type and skin type)ย 

Phase 3: refinement and blending (ULTRA, targeted touch-ups, pigment-focused care)ย 

If scars include significant tethering, we may also discuss scar release techniques asย appropriate, since lasers alone cannot fully lift scars anchored by fibrous bands.ย 

How Many Treatments Will You Need for Acne Scar Reduction?ย 

Most patients see meaningful improvement over 3โ€“6 months, with continued collagen remodeling for months after the final session.ย 

General guide:

Mild scars: often 3โ€“4 total sessions (ULTRA and/or RF microneedling)

Moderate scars: often 4โ€“6 sessions, usually mixed modalitiesย 

Severe scars: often 6+ sessions across a longer plan, usually including fractional CO2ย 

We set expectations around improvement, not perfection. A realistic goal for many patients sits in the 30โ€“70% improvement range, depending on scar depth, scar age, skin biology, and plan adherence.ย 

Downtime and โ€œSocial Recoveryโ€ย 

ULTRA: typically minimal, often a few days of mild redness/drynessย ย 

RF microneedling: usually a few days, sometimes longer depending on depth/energyย ย 

Fractional CO2: most downtime, commonly about 1 week or more depending on intensityย ย 

If you need low downtime, we build a plan around RF microneedling + ULTRA, then reserve CO2 for a single higher-impact session when timing works.ย 

Who is a good candidate for acne scar treatments?

You are a strong candidate if you have stable acne control, can protect skin from sun, and can follow a structured aftercare plan.ย 

We proceed more carefully (or choose different settings/modalities) if you have:ย 

  • Recent isotretinoin use (timing depends on dose, duration, and planned procedure)ย 
  • History of keloids or poor wound healingย 
  • Melasma tendency or high PIH risk without capacity for strict sun avoidanceย 
  • Uncontrolled acne, picking behavior, or active dermatitisย 

For RF microneedling specifically, deviceย selectionย and providerย expertiseย matter because FDA has reported serious complications with certain uses.ย ย 

How much does acne scar reduction cost?

Pricing varies for acne scar treatments based on device, treatment area, intensity, and number of sessions. In most markets, fractional CO2 sessions tend to cost more than ULTRA, with RF microneedling often in between.

Come in for a free consultation so we can assess your acne scarring, determine the right approach for you, and provide a pricing quote and treatment timeline.

To recap: Acne scar reduction often requires a multi-pronged approach.

If you want the best laser treatment for acne scars, do not chase a single โ€œbest device.โ€ Chase the best plan.

Acne scarring is multi-layered, so results improve most when we combine modalities: eCO2 for deep texture remodeling, RF microneedling for dermal collagen and contour change, and ULTRA for refinement and blending.

When we match the tool to the scar typeโ€”and keep safety, skin tone, and downtime in viewโ€”patients usually get smoother texture, better tone, and a more confident look without unnecessary risk.ย 

Dr. David LaMond 
Medical Director, Dermablue 

Frequently Asked Questions About Treatments for Acne Scarring

Which treatment works fastest for acne scars?

Fractional CO2 often produces the biggestย single-step change in texture for treating acne scarring, with the most downtime.ย 

Which acne scar treatment has the least downtime?

ULTRA usually wins for minimal downtime while still improving tone and fine texture.

Is RF microneedling safe?

It can be safe and effective when performed by well-trained medical professionals usingย appropriate devicesย and parameters. The FDA safety communication highlights potential serious risks reported with certain uses, so providerย selectionย is notย optional.)

Can lasers fix ice pick scars?

Ice pick scars often need targeted approaches. Lasers can soften their appearance, but deep narrow scars may needย additionalย techniques for best correction.

dr david lamond, medical director of dermablue, dermatology asheville

AUTHOR OF THE ARTICLE
Dr. David LaMond, D.O.

Dr. LaMond is a nutrition, hormone and prevention expert. Drawing from his foundation and board certification in Family Medicine, he has created the core medical principles behind the blue sky concept of total patient care…

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