Bioactive Fillers

Are you beginning to see laugh lines and wrinkles appearing on your skin but don’t want to risk the unnatural appearance that comes with typical cosmetic treatments? If so, a bioactive fille treatment could be the solution.

Bioactive fillers through DermaBlue help our patients achieve a younger, healthier look by stimulating natural collagen production in targeted areas.

Younger-Looking Skin
Bioactive fillers are specially-designed to smooth moderate-to-severe facial wrinkles and folds in order to create healthier and younger-looking skin.

Safe Administration
DermaBlue has established itself as a bioactive filler administration center with a long track record of safe and successful treatments for patients of all ages.

Simple, Pain-Free, and Effective
Unlike similar treatments, bioactive fillers stimulate natural collagen production within the skin to produce younger, healthier-looking skin in a safe and non-invasive manner.

How It Works

When it comes to skin health, much of your appearance comes down to how much of the protein collagen is present. High collagen levels give skin strength and elasticity while replacing dead skin cells, acting like glue to keep the skin together and create a healthier, fuller look.

As you age, you lose about a tablespoon of volume of bone in your face – bioactive fillers replace this lost volume with a tablespoon of filler to replace the bone as well as structural loss to the face.

While collagen is naturally-occurring throughout the body, production slows down as we age.

Unlike hyaluronic acid fillers, bioactive fillers counteract the aging process by stimulating natural collagen production within the patient’s body, building collagen levels over time. 

Bioactive fillers are generally longer-acting than other, similar treatments. Once injected, bioactive fillers stay active within the skin for 15 years, meaning that a one-time treatment can help you look and feel younger for years to come.

Types of Bioactive Fillers

DermaBlue offers treatments using the following fillers:


Bellafill is the only dermal filler that stimulates collagen growth long term to help maintain your youthful appearance for up to 5 years. Now, you can look your best without wasting time and money on frequent filler injections.

Bellafill’s tiny, polymethyl methacrylate (PMMA) microspheres are suspended within a base of smooth collagen gel. Once injected, the collagen gel immediately reduces the look of smile lines. Over time, your body uses the microspheres in Bellafill to create a “scaffold” onto which your own natural collagen can develop. This collagen forms a foundation that adds volume to wrinkles, reducing their appearance – and giving you natural-looking results that feel soft and smooth for up to 5 years.

Bellafill® is the only long-term filler that’s FDA approved to treat distensible acne scars for longer than one year. In just one office visit, you can safely treat your acne scars and leave feeling confident that you’ll look your best long-term.

At DermaBlue, we use Bellafill for nasolabial folds, cheek, forehead, neck and acne scarring.  It is our filler of choice for long-lasting, natural results for those who want total transformation.

Bellafill lasts up to 5 or more years.



Is a wrinkle filler used to plump the skin. This is our favorite filler to restore cheek volume and restore loss of facial volume due to normal facial bone loss due to aging.   Over time, the benefits of RADIESSE continue by stimulating your body’s own natural collagen. The natural results have been shown to last a year or more in many patients, making the treatment results both immediate and long lasting.  RADIESSE has been used for over a decade and has a long track record of safety and efficacy.

RADIESSE is used in total facial rejuvenation and can be used to reshape or create an ‘non surgical’ implant like look to reshape noses, chins, restore volume in hands or anywhere you would like long lasting, natural results.

RADIESSE lasts one year or longer and stimulates natural collagen formation.



Sculptra Aesthetic is an FDA-approved injectable that helps gradually replace lost collagen, an underlying cause of facial aging, for results which last more than two years. It’s used to correct shallow to deep facial wrinkles and folds and has been used almost anywhere to replace lost volume or to create volume where more is desired.  This is the product Kim Kardashian made famous with her non-surgical ‘butt lift’ and yes, we can do that too!

Sculptra Aesthetic is used in facial rejuvenation, acne scarring and body lifting, like non-surgical butt lifts.

Sculptra lasts 2 or more years and stimulates natural collagen formation.

Why DermaBlue for Bioactive Filler Treatment

DermaBlue is the premier center for bioactive filler treatment across the greater-Asheville area. While bioactive filler treatments typically require significant experience on the part of the administrator in order to be carried out safely and effectively, DermaBlue has a long track record of success in the field. We have even become a national training center for bioactive fillers, specifically BellaFill.

Is Bioactive Filler Treatment Right for Me?

Bioactive filler treatments are a great option for patients looking to increase their skin and bone health in a more natural way than can be obtained using hyaluronic filler treatments. Bioactive fillers are especially effective for patients in need of filler after having a facelift in order to rebuild the scaffolding of their facial structure.


Pricing for bioactive fillers varies by the specific filler being used, the application area, and the needs of the individual. Contact us today for details and find out if bioactive filler treatment is right for you!

Lift or accentuate your focus features with fillers, thread lifts, and ultherapy.

Hyaluronic Fillers

Hyaluronic fillers can be a great option for first-time filler users because they produce immediate results and can be dissolved in a matter of days if necessary. Get healthier, younger looking skin.

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Ultherapy helps to counteract the effects of time and gravity on your neck and face.  This amazing 60 minute in-office treatment helps to stimulate collagen in your neck and face and to help tighten and smooth skin.

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Thread Lifts

Lift and tighten your sagging features with threads that are placed into the deep tissue of your skin. The threads eventually dissolve, but the tissue will remain tight due to new collagen growth.

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